it really changes the way you colonize. In any game with it, first thing I'd do would be to send a large deep with starbase mins and some cash to the nearest cluster.
and If you want to put in a bit of extra effort, you can boost your supply production by quite a bit, by sending the colonists to a different base each turn and maxing factories.
Wirklich reich ist, wer mehr | Truly rich is, who holds
Träume in seiner Seele hat, | more dreams in his soul
als die Realität zerstören kann.| than reality can destroy.